Review and clinical update on parenteral nutrition-associated liver disease.

  title={Review and clinical update on parenteral nutrition-associated liver disease.},
  author={Emma M. Tillman},
  journal={Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition},
  volume={28 1},
Parenteral nutrition-associated liver disease (PNALD) is a complex disease that is diagnosed by clinical presentation, biochemical markers of liver injury, concurrent use of parenteral nutrition (PN), and negative workup for other causes of liver disease. Since the first case of PNALD was reported more than 30 years ago, clinicians have had few effective treatments for PNALD, and when disease progressed to liver cirrhosis, it was historically associated with poor outcomes. Within the past 5… CONTINUE READING
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