Review

@article{Krouk2018Review,
  title={Review},
  author={Dean Krouk},
  journal={Ibsen Studies},
  year={2018},
  volume={18},
  pages={194 - 199}
}
The co-authors of Ibsen, Scandinavia and the Making of a World Drama are both prominent figures in contemporary Ibsen studies. The historian Narve Fulsås was the editor of the four volumes of Ibsen’s letters for Henrik Ibsens skrifter, the recent critical edition published from 2005 to 2010, and the literary scholar Tore Rem has been the general editor of the newly translated Penguin Classics editions of Ibsen dramas. At the end of their collaborative study, Fulsås and Rem write that they have… 

References

SHOWING 1-10 OF 68 REFERENCES
Gene Mutations and Genomic Rearrangements in the Mouse as a Result of Transposon Mobilization from Chromosomal Concatemers
TLDR
The results suggest that the Sleeping Beauty system could be used in a forward-genetic approach to recover interesting phenotypes, but that local chromosomal rearrangements should be anticipated in conjunction with single-copy, local transposon insertions in chromosomes.
Tgfβ Signal Inhibition Cooperates in the Induction of iPSCs and Replaces Sox2 and cMyc
TLDR
It is demonstrated that inhibition of Tgfbbeta signaling cooperates in the reprogramming of murine fibroblasts by enabling faster, more efficient induction of iPSCs, whereas activation of T gfbeta signaling blocks reprograming.
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution.
TLDR
Genome-wide analysis of two key histone modifications indicated that iPS cells are highly similar to ES cells, and data show that transcription factor-induced reprogramming leads to the global reversion of the somatic epigenome into an ES-like state.
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse.
TLDR
Using doxycycline-inducible vectors, it is shown that exogenous factors are required for about 10 days, after which cells enter a self-sustaining pluripotent state and markers are identified that define cell populations prior to and during this transition period.
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells.
TLDR
It is shown that the orphan nuclear receptor Nr5a2 (also known as Lrh-1) can replace Oct4 in the derivation of iPSCs from mouse somatic cells, and it can also enhance reprogramming efficiency.
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
TLDR
It is shown that iPS cells can be efficiently differentiated into neural precursor cells, giving rise to neuronal and glial cell types in culture and demonstrating the therapeutic potential of directly reprogrammed fibroblasts for neuronal cell replacement in the animal model.
Reprogramming of murine and human somatic cells using a single polycistronic vector
TLDR
A novel approach to reduce the number of viruses necessary to reprogram somatic cells by delivering reprogramming factors in a single virus using 2A “self-cleaving” peptides, which support efficient polycistronic expression from a single promoter.
Generation of germline-competent induced pluripotent stem cells
TLDR
iPS cells competent for germline chimaeras can be obtained from fibroblasts, but retroviral introduction of c-Myc should be avoided for clinical application.
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
TLDR
This work shows that the orphan nuclear receptor Esrrb functions in conjunction with Oct4 and Sox2 to mediate reprogramming of mouse embryonic fibroblasts (MEFs) to iPS cells, and indicates that it is possible to reprogram MEFs without exogenous Klf transcription factors and link a nuclear receptor to somatic cell reprograming.
Polycistronic Lentiviral Vector for “Hit and Run” Reprogramming of Adult Skin Fibroblasts to Induced Pluripotent Stem Cells
TLDR
The results suggest that a single, polycistronic “hit and run” vector can safely and effectively reprogram adult dermal fibroblasts into iPS cells.
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