Review Article: Systemic conditions associated with areca nut usage: A literature review

@article{Javed2010ReviewAS,
  title={Review Article: Systemic conditions associated with areca nut usage: A literature review},
  author={F. Javed and Fernanda O Bello Correra and Milisha Chotai and Anwar R Tappuni and Khalid Almas},
  journal={Scandinavian Journal of Public Health},
  year={2010},
  volume={38},
  pages={838 - 844}
}
Aim: The adverse effects of areca nut (AN) chewing habit on oral health have been reported. However, the hazards related to the habit are not restricted to the oral cavity but they can also jeopardise the systemic health. Since no review reporting the harmful effects of AN chewing on systemic health is yet available, the aim of the present study was to review the systemic conditions associated with AN usage. Methods: To address the focused question ‘‘What are the deleterious effects of AN usage… 
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56 Citations
Highly Influential Citations
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Background Citations
14
Methods Citations
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56 Citations

Citation Type

Citation Type

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TLDR
The findings suggest the existence of mechanistic effects of areca nut chewing on CMDs exerted through multiple pathways that may interact with pre-existing biophysiological abnormalities.
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Areca nut chewers and healthy individuals in Karachi, Pakistan have a significant association with systemic inflammation and are two times more likely to have an elevated CRP as compared to raw areca nut users.
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TLDR
Subjects with habit of betel nut chewing were associated with an increased risk of colorectal polyps in Taiwanese general population and Screening for betel Nut chewing history and encouraging cessation might offer improved quality of life.
The role of diet in renal cell carcinoma incidence: an umbrella review of meta-analyses of observational studies
TLDR
No high-quality evidence exists in the overall analysis of systematic reviews or meta-analyses that assessed associations between dietary factors and RCC, and moderate drinking and cruciferous vegetables might be beneficial for Europeans and North Americans, but the results should be interpreted with caution.
Predictors of the severity of oral submucous fibrosis among gutka consumers: a regression analysis.
Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease
TLDR
This study suggests that betel nut chewing is associated with the risk of KSD and warrants further attention to this problem.
Areca Nut Chewing: Initiation, Addiction, and Harmful Effects Emphasizing the Barriers and Importance of Cessation
TLDR
Behavior changing interventions proved to be more effective in areca nut cessation, but recently studies on pharmacological therapies are also emerging.
Consumption of Areca Nut During Pregnancy and its Effects on Newborns
TLDR
It would be important to advise pregnant women against the consumption of areca nut in any of its forms, as along with adverse outcomes, the presence of arecoline has been studied not only in pregnant women but also in neonatal biological matrices as meconium, cord blood and urine.
Prevalence of non-communicable diseases and their risk factors in Papua New Guinea: A systematic review
TLDR
Variations in the prevalence of non-communicable diseases and their risk factors attributed to the lifestyle and genetic diversity of the Papua New Guinea population are demonstrated.
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References

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Areca nut chewing and mortality in an elderly cohort study.
TLDR
It is found that, although betel quid chewing resulted in a statistically significant increase in the risk of total and cerebrovascular deaths in the elderly population, the associations were weak and should be interpreted with caution.
A population-based study of the association between betel-quid chewing and the metabolic syndrome in men.
TLDR
Independent predictive dose-response effects of betel-quid chewing for the metabolic syndrome and its components in a population-based study of men with a 15% prevalence of betle-nut chewing suggest dose- response effects.
Betel-quid use is associated with the risk of the metabolic syndrome in adults.
TLDR
The daily rate of betel-quid use is independently and positively associated with the metabolic syndrome in adults and was not associated with low HDL cholesterol or hyperglycemia.
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TLDR
Although betel nut chewing is widespread, significant toxicity as reported to a poison center is rare and the incidence of such events is likely to be underreported.
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TLDR
The association between betel-nut use and CKD is independent of age, BMI, smoking, alcohol consumption, hypertension, diabetes and hyperlipidaemia.
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TLDR
Betelnut use is associated with chronic kidney disease in adults younger than 65 and multivariate logistic regression with adjustment for age, sex, hypertension, and diabetes found it independently associated with CKD.
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TLDR
In subjects without T2D, gutka-chewers have severe periodontal conditions and oral symptoms compared to non-Chewers, while in subjects with T1D, the severity of these variables is related to glycemic levels rather than gutka consumption.
Betel nut chewing is associated with increased risk of cardiovascular disease and all-cause mortality in Taiwanese men.
TLDR
Greater frequency of betel nut chewing was associated with greater CVD and all-cause mortality in Taiwanese men, and an anti-betel nut chewers program is urgently warranted for current chewers.
Betel-quid use is associated with heart disease in women.
TLDR
Betel-quid use is independently associated with heart disease in women, and nonpregnant adults aged 20-64 y from the nationally representative Nutrition and Health Survey in Taiwan were studied for independent associations.
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