Review Article: Sleep, Pain and Cannabis

@article{Ferguson2015ReviewAS,
  title={Review Article: Sleep, Pain and Cannabis},
  author={G. Ferguson and Ware Ma},
  journal={Journal of sleep disorders and therapy},
  year={2015},
  volume={4},
  pages={1-5}
}
One of the most common reasons that patients report the use of cannabis for medical purposes is to reduce pain and improve sleep. Despite this repeated association, it is not clear whether the effects of cannabis use on pain are mediated by the effect of improved sleep, or vice versa. This distinction may have important therapeutic implications as different cannabis preparations have different pharmacokinetic properties; short acting cannabinoids may therefore initiate sleep but not maintain it… Expand

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References

SHOWING 1-10 OF 59 REFERENCES
Cannabis, Pain, and Sleep: Lessons from Therapeutic Clinical Trials of Sativex®, a Cannabis‐Based Medicine
TLDR
No tolerance to the benefit of Sativex on pain or sleep, nor need for dosage increases have been noted in safety extension studies of up to four years, wherein 40–50% of subjects attained good or very good sleep quality, a key source of disability in chronic pain syndromes that may contribute to patients' quality of life. Expand
Sleep disturbance and the effects of extended-release zolpidem during cannabis withdrawal.
TLDR
It is indicated that sleep disruption associated with cannabis withdrawal can be attenuated by zolpidem, suggesting that hypnotic medications might be useful adjunct pharmacotherapies in the treatment of cannabis use disorders. Expand
Cannabis use for chronic non-cancer pain: results of a prospective survey
TLDR
It is concluded that cannabis use is prevalent among the chronic non‐cancer pain population, for a wide range of symptoms, with considerable variability in the amounts used. Expand
How do sleep disturbance and chronic pain inter-relate? Insights from the longitudinal and cognitive-behavioral clinical trials literature.
TLDR
The literature suggests that the relationship between clinical pain and insomnia is reciprocal and CBT treatments for pain or insomnia hold promise in reducing pain severity and improving sleep quality. Expand
The effects of cannabinoid administration on sleep: a systematic review of human studies.
TLDR
Findings were mixed and showed various effects of cannabinoid administration on several aspects of sleep, however, Methodological issues in the majority of studies to date preclude any definitive conclusion. Expand
Using cannabis to help you sleep: heightened frequency of medical cannabis use among those with PTSD.
TLDR
Increased rates of coping-oriented use of cannabis and greater frequency of cannabis use among medical users with high PTSD scores compared with low PTSD scores are found, and sleep improvement appears to be a primary motivator for coping- oriented use. Expand
The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial
TLDR
Nabilone is effective in improving sleep in patients with FM and is well tolerated, and low-dose nabilone given once daily at bedtime may be considered as an alternative to amitriptyline. Expand
Cannabis for therapeutic purposes: patient characteristics, access, and reasons for use.
TLDR
Results indicate a substantial disconnect between the therapeutic use of cannabis and research on the risks and benefits of such use; particularly with regard to the anxiolytic and sedative use of marijuana. Expand
Cannabis for migraine treatment: the once and future prescription? An historical and scientific review
TLDR
Control clinical trials of Cannabis in acute migraine treatment are warranted and ethnobotanical and anecdotal references continue to refer to its efficacy for this malady. Expand
Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ‘N of 1’ studies
TLDR
A total of 34 ‘N of 1’ studies were undertaken using this novel therapy for patients with chronic, mainly neuropathic, pain and associated symptoms to explore efficacy, tolerability, safety and dosages of CBME. Expand
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