Review: the approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic.

@article{Rajakovi2012ReviewTA,
  title={Review: the approaches for estimation of limit of detection for ICP-MS trace analysis of arsenic.},
  author={Ljubinka V Rajakovi{\'c} and Dana D Markovi{\'c} and Vladana N Rajakovi{\'c}-Ognjanovi{\'c} and Davor Antanasijevi{\'c}},
  journal={Talanta},
  year={2012},
  volume={102},
  pages={
          79-87
        }
}
The analytical properties of an analytical method must be evaluated through validation protocols. Beside specificity and/or selectivity, linearity of calibration, repeatability and accuracy, the most important parameters are: LOD (limit of detection) and LOQ (limit of quantification). Through these limits, it is possible to define the smallest concentration of analyte that can be reliably detected and quantified. To establish these limits, an analyst should apply several estimation methods and… CONTINUE READING
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