Review: nuclear events in apoptosis.

  title={Review: nuclear events in apoptosis.},
  author={John D. Robertson and Sten Orrenius and Boris Zhivotovsky},
  journal={Journal of structural biology},
  volume={129 2-3},
Initial apoptosis research characterized this form of cell death based on distinct nuclear morphology that was subsequently shown to be associated with the appearance of oligonucleosomal DNA fragments. More recent evidence has indicated that apoptosis depends upon a tightly regulated cellular program for its successful initiation and execution. Molecular participants in this program are present in different subcellular compartments, including the plasma membrane, cytosol, mitochondria, and… CONTINUE READING