Review: emerging developments in the use of bioactive glasses for treating infected prosthetic joints.

@article{Rahaman2014ReviewED,
  title={Review: emerging developments in the use of bioactive glasses for treating infected prosthetic joints.},
  author={Mohamed N. Rahaman and B Sonny Bal and Wenhai Huang},
  journal={Materials science & engineering. C, Materials for biological applications},
  year={2014},
  volume={41},
  pages={
          224-31
        }
}
Bacterial contamination of implanted orthopedic prostheses is a serious complication that requires prolonged systemic antibiotic therapy, major surgery to remove infected implants, bone reconstruction, and considerable morbidity. Local delivery of high doses of antibiotics using poly(methyl methacrylate) (PMMA) cement as the carrier, along with systemic antibiotics, is the standard treatment. However, PMMA is not biodegradable, and it can present a surface on which secondary bacterial infection… CONTINUE READING
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