Review: cytokine involvement in ovarian processes.

  title={Review: cytokine involvement in ovarian processes.},
  author={Paul F. Terranova and Valerie Montgomery Rice},
  journal={American journal of reproductive immunology},
  volume={37 1},
PROBLEM Expression of tumor necrosis factor-alpha (TNF) and interleukins 1 alpha and 1 beta (IL-1) have been reported in ovaries of several species and humans and are implicated in ovarian follicular development and atresia, ovulation, steroidogenesis, and corpus luteum function (including formation, development, and regression). The principal abnormal processes affected by these cytokines are ovarian cancer and reduction of ovarian function during sepsis. METHODS A literature review… CONTINUE READING
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