Review: Tauopathy in the retina and optic nerve: does it shadow pathological changes in the brain?

@inproceedings{Ho2012ReviewTI,
  title={Review: Tauopathy in the retina and optic nerve: does it shadow pathological changes in the brain?},
  author={Wing-Lau Ho and Yen Leung and Andrea Wing-Ting Tsang and Kwok-fai So and K W K Chiu and Raymond Chuen-Chung Chang},
  booktitle={Molecular vision},
  year={2012}
}
Tau protein's versatility lies in its functions within the central nervous system, including protein scaffolding and intracellular signaling. Tauopathy has been one of the most extensively studied neuropathologies among the neurodegenerative diseases. Because the retina and optic nerve are parts of the central nervous system, we hypothesize that tauopathy also plays a role in various eye diseases. However, little is known about tauopathy in the retina and optic nerve. Here, we summarize the… CONTINUE READING

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