Review: Retinal degeneration: Focus on the unfolded protein response

  title={Review: Retinal degeneration: Focus on the unfolded protein response},
  author={Marina S. Gorbatyuk and Oleg S Gorbatyuk},
  booktitle={Molecular vision},
Recently published literature has provided evidence that the unfolded protein response (UPR) is involved in the development of retinal degeneration. The scope of these studies encompassed diabetic retinopathy, retinopathy of prematurity, glaucoma, retinal detachment, light-induced retinal degeneration, age-related macular degeneration, and inherited retinal degeneration. Subsequent studies investigating the role of individual UPR markers in retinal pathogenesis and examining the therapeutic… CONTINUE READING
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