Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era

@article{Behrens2017ReviewCS,
  title={Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era},
  author={Edward M. Behrens and Gary A. Koretzky},
  journal={Arthritis \& Rheumatology},
  year={2017},
  volume={69}
}
“Cytokine storm syndrome” is a diverse set of conditions unified by a clinical phenotype of systemic inflammation, multi-organ failure, hyperferritinemia, and, if untreated, often death. This clinical constellation is caused by the elaboration of extreme amounts of inflammatory mediators resulting from unchecked feedforward immune activation and amplification. The initiating factors leading to the end state of cytokine storm are heterogeneous and derive from rheumatologic, oncologic, and… 
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