Review: Artificial liver support systems.

  title={Review: Artificial liver support systems.},
  author={Andreas Kamlot and Jacek Rozga and F D Watanabe and Achilles A. Demetriou},
  journal={Biotechnology and bioengineering},
  volume={50 4},
Despite recent advances in medical therapy, patients with fulminant hepatic failure (FHF) have a mortality rate approaching 90%. Many patients die because of failure to arrest the progression of cerebral edema. Liver transplantation has improved survival to 65% to 75%. However, there is a shortage of donors and approximately one half of the patients with FHF will die while awaiting liver transplantation. There is thus a need to develop an extracorporeal liver assist system to help keep these… CONTINUE READING

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