Reversing acute bronchoconstriction in asthma: the effect of bronchodilator tolerance after treatment with formoterol.

@article{Jones2001ReversingAB,
  title={Reversing acute bronchoconstriction in asthma: the effect of bronchodilator tolerance after treatment with formoterol.},
  author={Sarah A. Jones and Jan Cowan and Erin M. Flannery and Robert J Hancox and G. Peter Herbison and D. Robin Taylor},
  journal={The European respiratory journal},
  year={2001},
  volume={17 3},
  pages={368-73}
}
Continuous treatment with a short-acting beta2-agonist can lead to reduced bronchodilator responsiveness during acute bronchoconstriction. This study evaluated bronchodilator tolerance to salbutamol following regular treatment with a long-acting beta2-agonist, formoterol. The modifying effect of intravenous corticosteroid was also studied. Ten asthmatic subjects (using inhaled steroids) participated in a randomised, double-blind, placebo-controlled, cross-over study. Formoterol 12 microg b.i.d… CONTINUE READING
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