Corpus ID: 99712683

Reversible spermatoxic effect of Andrographis paniculata methanol extract in Sprague Dawley rats

  title={Reversible spermatoxic effect of Andrographis paniculata methanol extract in Sprague Dawley rats},
  author={Khaidatul Akmar Kamaruzaman and Mahanem Mat Noor},
  journal={Malaysian applied biology},
Andrographis paniculata is a herbal plant in the Acanthaceae family with potential to treat diabetes and cardiovascular and as an antifertility agent. The purpose of this study was to determine the reversible antifertility effect of methanol extract A. paniculata on sperm quality and spermatogenesis. A total of 28 male Sprague Dawley rats were assigned into two groups; control group (K1) and treated group (K2) with 14 rats in each group. The treated group was force-fed with a dose of 800 mg… Expand

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