Reversible posterior leukoencephalopathy syndrome after carboplatin therapy.

@article{Vieillot2006ReversiblePL,
  title={Reversible posterior leukoencephalopathy syndrome after carboplatin therapy.},
  author={Sabine Vieillot and Damien Pouessel and Nicolas Menjot de Champfleur and Charles Becht and St{\'e}phane Culine},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2006},
  volume={18 3},
  pages={
          608-9
        }
}
A 53-year-old woman presented in September 2004 with a stage IV adenocarcinoma in the upper lobe of the left lung with pleuropulmonary metastasis. She was treated with cisplatin (70 mg/m 2 on day 1 and gemcitabine 1250 mg/m 2 on days 1 and 8) by intravenous administration every 3 weeks. After five treatment cycles, the administration of cisplatin was stopped because of a low clearance creatinin, 60 ml/min. The cumulative dose of cisplatin at that point was 350 mg/m 2. The sixth course included… CONTINUE READING

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