Reversible low-molecular-weight proteinuria in patients with distal renal tubular acidosis

  title={Reversible low-molecular-weight proteinuria in patients with distal renal tubular acidosis},
  author={Takashi Igarashi and Hidehiko Kawato and Shigehiko Kamoshita},
  journal={Pediatric Nephrology},
Four patients with untreated renal tubular acidosis had a urinary excretion of low-molecular-weight (LMW) proteins which was restored to normal by alkali therapy. Hypokalaemic proximal tubular damage in untreated patients with distal renal tubular acidosis is believed to be the cause of LMW proteinuria. An examination of urinary excretion of LMW proteins is useful for determining hypokalaemic proximal tubular dysfunction, as well as the efficiency of alkali therapy. 


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Proximal renal tubular dysfunction in primary distal renal tubular acidosis

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