Reversible lesions of the rhinal cortex produce delayed non-matching-to-sample deficits in rats.

Abstract

Rats with cannulae guides implanted in the rhinal cortex were tested on a delayed non-matching-to-sample task, following either lidocaine or sham microinfusions. Bilateral lidocaine microinfusions to the rhinal cortex produced significant delayed non-matching-to-sample deficits. These results are consistent with the putative role of the rhinal cortex in object recognition but because the deficits were not shown to be time dependent, non-mnemonic interpretations cannot be ruled out. These results also illustrate the utility of reversible lidocaine lesions in the study of the neuroanatomical basis of delayed non-matching-to-sample.

Cite this paper

@article{Barnes2000ReversibleLO, title={Reversible lesions of the rhinal cortex produce delayed non-matching-to-sample deficits in rats.}, author={Steven J. Barnes and Stan B Floresco and Tom J Kornecook and John P. J. Pinel}, journal={Neuroreport}, year={2000}, volume={11 2}, pages={351-4} }