Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease

@article{Kleopa2005ReversibleIA,
  title={Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease},
  author={Kleopas A Kleopa and Kyriacos C. Kyriacou and Eleni Zamba-Papanicolaou and Theodoros Kyriakides},
  journal={Muscle \& Nerve},
  year={2005},
  volume={31}
}
We report a patient with late‐onset celiac disease and neurological manifestations including myopathy, polyneuropathy, and ataxia. Laboratory investigations showed anti‐gliadin antibodies and severe vitamin E deficiency. Muscle biopsy revealed inflammatory infiltrates and rimmed vacuoles, similar to those found in inclusion‐body myositis. A gluten‐free diet and vitamin E supplementation reversed both the clinical neurological manifestations and the abnormalities in the muscle biopsy. Anti… 
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