Reversible inactivation of the lateral hypothalamus reversed high reward choices in cost-benefit decision-making in rats

@article{Karimi2017ReversibleIO,
  title={Reversible inactivation of the lateral hypothalamus reversed high reward choices in cost-benefit decision-making in rats},
  author={Sara Shaeri Karimi and Azam Mesdaghinia and Zahra Farzinpour and Gholamali Hamidi and Abbas Haghparast},
  journal={Neurobiology of Learning and Memory},
  year={2017},
  volume={145},
  pages={135-142}
}
The Lateral hypothalamus (LH) is an important component of the networks underlying the control of feeding and other motivated behaviors. Cost-benefit decision-making is mediated largely by the prefrontal cortex (PFC) which strongly innervates the LH. Therefore, in the current study, we conducted a series of experiments to elucidate the role of the perifornical area of the lateral hypothalamus (PeF-LH) in effort and/or delay-based decision-making. We trained different groups of rats in a delay… CONTINUE READING
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