Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat.

@article{Norreel2003ReversibleDO,
  title={Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat.},
  author={J C Norreel and Jean-François Pflieger and Edouard Pearlstein and Juliette Simeoni-Alias and F Clarac and Laurent Vinay},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2003},
  volume={23 5},
  pages={1924-32}
}
The central pattern generators (CPGs) for locomotion, located in the lumbar spinal cord, are functional at birth in the rat. Their maturation occurs during the last few days preceding birth, a period during which the first projections from the brainstem start to reach the lumbar enlargement of the spinal cord. The goal of the present study was to investigate the effect of suppressing inputs from supraspinal structures on the CPGs, shortly after their formation. The spinal cord was transected at… CONTINUE READING