Reversible changes in the testes and epididymides of dog treated with alpha-chlorohydrin.

@article{Dixit1975ReversibleCI,
  title={Reversible changes in the testes and epididymides of dog treated with alpha-chlorohydrin.},
  author={Vineeta Dixit and Nirmal Kumar Lohiya and Manish Arya and Madhoolika Agrawal},
  journal={Acta biologica et medica Germanica},
  year={1975},
  volume={34 11-12},
  pages={1851-6}
}
1. Chronic administration of alpha-chlorohydrin (8 mg/kg body wt for 30 days) caused lesions in the testis of dog. The changes in the germ cells were degenerative. The seminiferous tubule and Leydig cell nuclear diameter were reduced. 2. Epididymal cell height was greatly reduced and the stereocilia had disappeared completely. The lumen was devoid of spermatozoa. 3. Alpha-chlorohydrin administration inhibited the RNA and sialic acid contents in the testes and epididymides of dog. Total… CONTINUE READING