Reversible changes in Ca(2+)-activation properties of rat skeletal muscle exposed to elevated physiological temperatures.

@article{Poel2002ReversibleCI,
  title={Reversible changes in Ca(2+)-activation properties of rat skeletal muscle exposed to elevated physiological temperatures.},
  author={Chris van der Poel and D George Stephenson},
  journal={The Journal of physiology},
  year={2002},
  volume={544 3},
  pages={
          765-76
        }
}
Exposure of relaxed rat extensor digitorum longus (EDL; predominantly fast-twitch) muscle to temperatures in the upper physiological range for mammalian skeletal muscle (43-46 degrees C) led to reversible alterations of the contractile activation properties. These properties were studied using the mechanically skinned fibre preparation activated in Ca(2+)-buffered solutions. The maximum Ca(2+)-activated force (maximum force per cross-sectional area) and the steepness of force-pCa (-log(10)[Ca(2… CONTINUE READING
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