Reversible blockage of neurite development and growth cone formation in neuronal cultures of a temperature-sensitive mutant of Drosophila.

Abstract

It has been suggested that the membrane recycling process in the Drosophila mutant shibirets1 (shits1) is reversibly blocked at restrictive temperature (greater than 29 degrees C) in various cell types, including neurons, as a result of enhanced vesicle fusion and disrupted membrane pinch-off (Poodry and Edgar, 1979; Koenig et al., 1983; Kosaka and Ikeda… (More)

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