Reversible acetylation on Lys501 regulates the activity of RNase II

Abstract

RNase II, a 3' to 5' processive exoribonuclease, is the major hydrolytic enzyme in Escherichia coli accounting for ∼90% of the total activity. Despite its importance, little is actually known about regulation of this enzyme. We show here that one residue, Lys501, is acetylated in RNase II. This modification, reversibly controlled by the acetyltransferase… (More)
DOI: 10.1093/nar/gkw053

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