Reversibility of GERD Ultrastructural Alterations and Relief of Symptoms After Omeprazole Treatment

@article{Calabrese2005ReversibilityOG,
  title={Reversibility of GERD Ultrastructural Alterations and Relief of Symptoms After Omeprazole Treatment},
  author={Carlo Calabrese and M Bortolotti and Anna Fabbri and Alessandra Areni and Giovanna Cenacchi and Carlo Scialpi and Mario Miglioli and Giulio Di Febo},
  journal={The American Journal of Gastroenterology},
  year={2005},
  volume={100},
  pages={537-542}
}
BACKGROUND:Dilation of intercellular spaces (DIS) of human esophageal epithelium, evident at transmission electron microscopy (TEM), is an early marker of damage caused by gastroesophageal reflux, but its reversibility after therapy has not been investigated.AIM:To evaluate whether omeprazole can induce the healing of DIS.METHODS:Thirty-eight symptomatic patients, 22 with nonerosive reflux disease (NERD) and 16 with erosive esophagitis (EE), classified on the basis of 24-h pH monitoring, were… CONTINUE READING
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Diagnostic value of histology in non-erosive gastroesophageal reflux disease

  • NE Schindlbeck, B Weibecke, AG Klauser
  • Gut
  • 1996
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