Reverse transcriptase polymerase chain reaction on fine needle aspirates for rapid detection of translocations in synovial sarcoma.

@article{Nilsson1998ReverseTP,
  title={Reverse transcriptase polymerase chain reaction on fine needle aspirates for rapid detection of translocations in synovial sarcoma.},
  author={Gwen Nilsson and Ming-rong Wang and Johan Wejde and Lena Kanter and Jonas Karl{\'e}n and Emi Tani and Andris Kreicbergs and Olle Larsson},
  journal={Acta cytologica},
  year={1998},
  volume={42 6},
  pages={1317-24}
}
OBJECTIVE To evaluate the utilization of fine needle aspiration (FNA) biopsy to obtain material for reverse-transcriptase polymerase chain reaction (RT-PCR) in the detection of the t(X;18)(p11.2;q11.2) translocation in synovial sarcomas. STUDY DESIGN We applied RT-PCR to detection of synovial sarcoma fusion gene transcripts on fine needle aspirates. Five clinical samples were first analyzed: one was a tumor previously diagnosed as malignant hemangiopericytoma, one was a poorly defined tumor… CONTINUE READING

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