Reverse signalling of membrane TNF in human natural killer cells: a comparison of the effect of certolizumab pegol and other anti-TNF agents

@inproceedings{Fossati2011ReverseSO,
  title={Reverse signalling of membrane TNF in human natural killer cells: a comparison of the effect of certolizumab pegol and other anti-TNF agents},
  author={Gianluca Fossati and Andrew M Nesbitt},
  booktitle={Journal of Translational Medicine},
  year={2011}
}
Introduction Differences have been seen among the anti-TNFs in mediating reverse signalling of membrane TNF-a (mTNF-a). Natural killer (NK) cells express high levels of mTNF-a and may be involved in rheumatoid arthritis pathogenesis. We examined the effect of certolizumab pegol (CZP) and the other anti-TNFs, adalimumab (ADA), etanercept (ETA) and infliximab (IFX), on cellular activities of NK cells.