Reverse-phase HPLC separation of D-amygdalin and neoamygdalin and optimum conditions for inhibition of racemization of amygdalin.

@article{Hwang2002ReversephaseHS,
  title={Reverse-phase HPLC separation of D-amygdalin and neoamygdalin and optimum conditions for inhibition of racemization of amygdalin.},
  author={Eun-Young Hwang and Je-Hyun Lee and Y Lee and S Hong},
  journal={Chemical & pharmaceutical bulletin},
  year={2002},
  volume={50 10},
  pages={1373-5}
}
In boiling aqueous solution, D-amygdalin usually begins to convert into neoamygdalin in 3 min and more than 30% of the initial D-amygdalin is found as neoamygdalin after 30 min. In this report, we establish methods for simple HPLC analysis and the inhibition of D-amygdalin conversion. D-Amygdalin and its conversion product, neoamygdalin, were clearly separated on reverse-phase column chromatography by an optimized eluent of 10 mM sodium phosphate buffer (pH 3.8) containing 6% acetonitrile… CONTINUE READING
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Inhibitiory Effects on the Conversion to Neoamygdalin with the Amount of Citric Acid When Extracting Amygdalin from Tōnin (a) 0.005% citric acid, (b) 0.05% citric acid, (c) 0.1% citric acid

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Deut. Chem. Ges., • 2002

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