Reverse engineering validation using a benchmark synthetic gene circuit in human cells.

Abstract

Multicomponent biological networks are often understood incompletely, in large part due to the lack of reliable and robust methodologies for network reverse engineering and characterization. As a consequence, developing automated and rigorously validated methodologies for unraveling the complexity of biomolecular networks in human cells remains a central… (More)
DOI: 10.1021/sb300093y

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