Reverse aqueous microemulsions in hydrofluoroalkane propellants and their aerosol characteristics.

@article{Selvam2012ReverseAM,
  title={Reverse aqueous microemulsions in hydrofluoroalkane propellants and their aerosol characteristics.},
  author={Parthiban Selvam and Balaji Bharatwaj and L Caracena Porcar and Sandro R. P. da Rocha},
  journal={International journal of pharmaceutics},
  year={2012},
  volume={422 1-2},
  pages={
          428-35
        }
}
In this work we describe the structure and environment of reverse aqueous microemulsions formed in 1,1,1,2-tetrafluoroethane (HFA134a) propellant in the presence of a non-ionic ethoxylated copolymer, and the aerosol characteristics of the corresponding pressurized metered dose inhaler (pMDI) formulations. The activity of selected polypropylene oxide-polyethylene oxide-polypropylene oxide (PO(m)EO(n)PO(m)) amphiphiles at the HFA134a-water interface was studied using in situ high-pressure… CONTINUE READING
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