Reverse Phase Thin Layer Chromatography of Aminoal- kanethiosulfuric Acids, Mercaptoalkanamines and Aminoalkyl Disulfides

Abstract

The experimental Rm values for a series of aminoalkanethiosulfuric acids, mercaptoalkanamines and aminoalkyl disulfides were determined by reverse phase thin layer chromatography. The Rm values were determined for various concentrations of methanol:water and the correlation obtained was extrapolated to 100% water. These values permitted the calculation of the log P values for each substance. The log P values obtained by this method were compared with those obtained using the shake-flask method and by theoretical calculations utilizing fragment constants.

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Cite this paper

@inproceedings{Cardoso2002ReversePT, title={Reverse Phase Thin Layer Chromatography of Aminoal- kanethiosulfuric Acids, Mercaptoalkanamines and Aminoalkyl Disulfides}, author={Maria das Graças Cardoso and David L. Nelson and Antonia T. do Amaral and Cust{\'o}dio Doni and zete dos Santos and Alcilene de Abreu Pereira and Ana Cl{\'a}udia Barneche de Oliveira}, year={2002} }