Reversal of the sleep/wake cycle disorder of sleeping sickness after trypanosomicide treatment.

@article{Buguet1999ReversalOT,
  title={Reversal of the sleep/wake cycle disorder of sleeping sickness after trypanosomicide treatment.},
  author={Alain Buguet and P. Tapie and Joel Bert},
  journal={Journal of sleep research},
  year={1999},
  volume={8 3},
  pages={225-35}
}
To determine whether the circadian disruption of the sleep/wake cycle observed in sleeping sickness, human African trypanosomiasis (HAT), can be reversed after trypanosomicide treatment, 10 Congolese patients infected by Trypanosoma brucei gambiense underwent 24-h polysomnographic recordings before treatment with melarsoprol and after each of three weekly treatment sessions. Polysomnography consisted of a continuous recording of the electroencephalogram, electromyogram and electro-oculogram on… CONTINUE READING

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