Reversal of the late phase of spike frequency adaptation in cat spinal motoneurons during fictive locomotion.

@article{Brownstone2011ReversalOT,
  title={Reversal of the late phase of spike frequency adaptation in cat spinal motoneurons during fictive locomotion.},
  author={Robert M. Brownstone and Sherry Krawitz and Larry M. Jordan},
  journal={Journal of neurophysiology},
  year={2011},
  volume={105 3},
  pages={
          1045-50
        }
}
In spinal motoneurons, late spike frequency adaptation (SFA) is defined as the slowing of the firing rate over tens of seconds and can be seen during sustained or intermittent current injection. Although the function of late SFA is not known, it may result in a decrease in force production over time, or muscle fatigue. Because locomotion can persist for long periods of time without fatigue, late SFA was studied using intracellular recordings from adult cat motoneurons during fictive locomotion… CONTINUE READING

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