Reversal of sedation with flumazenil in regional anaesthesia: a review.

Five authors have described safe and effective sedation-reversal with flumazenil in 150 patients where a benzodiazepine (BZ) was used to supplement regional anaesthesia. Problems of post-reversal anxiety seen with high-dose bolus flumazenil (0.1 mg kg-1) were not seen when flumazenil was titrated to effect and 1.0 mg not exceeded. Efficacy was also… CONTINUE READING