Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial.

@article{Blobner2010ReversalOR,
  title={Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial.},
  author={Manfred Blobner and Lars I. Eriksson and Jens Scholz and Johann Motsch and Giorgio della Rocca and M. Eric F. Prins},
  journal={European journal of anaesthesiology},
  year={2010},
  volume={27 10},
  pages={874-81}
}
BACKGROUND AND OBJECTIVE Sugammadex, a modified gamma-cyclodextrin, is a selective relaxant-binding agent designed to reverse the effects of the steroidal neuromuscular blocking agents rocuronium or vecuronium. This study compared the efficacy of sugammadex and neostigmine for reversal of neuromuscular blockade induced by rocuronium for facilitating elective surgery. METHODS This randomised, multicentre, parallel-group trial included 98 adult patients. Patients received intravenous propofol… CONTINUE READING

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