Reversal of rocuronium-induced neuromuscular block with sugammadex is faster than reversal of cisatracurium-induced block with neostigmine.

@article{Flockton2008ReversalOR,
  title={Reversal of rocuronium-induced neuromuscular block with sugammadex is faster than reversal of cisatracurium-induced block with neostigmine.},
  author={E A Flockton and Pasquale Mastronardi and Jennifer Hunter and Carmen Gomar and Rajinder K Mirakhur and Luciano Aguilera and Francesco Giunta and Claude Meistelman and M. Eric F. Prins},
  journal={British journal of anaesthesia},
  year={2008},
  volume={100 5},
  pages={622-30}
}
BACKGROUND Reversal of the residual effect of rocuronium or cisatracurium by neostigmine may be slow and associated with side-effects. This randomized, safety-assessor-blinded study compared the efficacy of sugammadex, a selective relaxant binding agent for reversal of rocuronium-induced neuromuscular block, with that of neostigmine for reversal of cisatracurium-induced neuromuscular block. The safety of sugammadex and neostigmine was also evaluated. METHODS Adult surgical patients (ASA class… CONTINUE READING