Reversal of plasticity-like effects in the human motor cortex.

  title={Reversal of plasticity-like effects in the human motor cortex.},
  author={Ying-Zu Huang and John C. Rothwell and C. S. Lu and Wen-Li Chuang and Wey-Yil Lin and Rou-Shayn Chen},
  journal={The Journal of physiology},
  volume={588 Pt 19},
A number of experiments in animals have shown that successful induction of plasticity can be abolished if an individually ineffective intervention is given shortly afterwards. Such effects are termed depotentiation/de-depression. These effects contrast with metaplasticity/homeostatic plasticity in which pretreatment of the system with one protocol modulates the response to a second plasticity-inducing protocol. Homeostatic plasticity maintains the balance of plasticity in the nervous system at… CONTINUE READING
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