Reversal of neuromuscular block.

  title={Reversal of neuromuscular block.},
  author={Abhishek Srivastava and Jennifer Hunter},
  journal={British journal of anaesthesia},
  volume={103 1},
The use of anticholinesterases to reverse residual neuromuscular block is efficacious only if recovery is already established. It was originally advised that at least the second twitch (T2) of the train-of-four response should be detectable before neostigmine is administered. Even in these circumstances, the full effect of anticholinesterases takes up to 10 min to achieve. Anticholinesterases also have muscarinic side-effects that require an antimuscarinic to be administered concomitantly. An… CONTINUE READING