Reversal of flunitrazepam with flumazenil: duration of antagonist activity.

Abstract

The duration of action, dose requirements and efficacy of flumazenil, a specific benzodiazepine antagonist, were evaluated in 50 patients scheduled for orthopaedic surgery under local anaesthesia and flunitrazepam sedation. Fifteen minutes after injection of flunitrazepam 0.03 mg kg-1 the patients received placebo or flumazenil i.v. in a randomized, double… (More)

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Cite this paper

@article{Claeys1988ReversalOF, title={Reversal of flunitrazepam with flumazenil: duration of antagonist activity.}, author={Myriam Claeys and Frederik Camu and Ione Jayce Ceola Schneider and Elisabeth Gepts}, journal={European journal of anaesthesiology. Supplement}, year={1988}, volume={2}, pages={209-17} }