Reversal of endothelial progenitor cell dysfunction in patients with type 2 diabetes using a conditioned medium of human embryonic stem cell-derived endothelial cells.

@article{Ho2012ReversalOE,
  title={Reversal of endothelial progenitor cell dysfunction in patients with type 2 diabetes using a conditioned medium of human embryonic stem cell-derived endothelial cells.},
  author={Jenny C. Y. Ho and Wing-Hon Kevin Lai and Ming-fang Li and K. T. P. Au and Mei-Chu Yip and Navy L. Y. Wong and Ethel Sau Kuen Ng and Francis Fu-Yuen Lam and Chung-wah Siu and Hung-fat Tse},
  journal={Diabetes/metabolism research and reviews},
  year={2012},
  volume={28 5},
  pages={462-73}
}
BACKGROUND The potential clinical application of bone marrow or peripheral blood-derived progenitor cells for cardiovascular regeneration in patients with diabetes mellitus (DM) is limited by their functional impairment. We sought to determine the mechanisms of impaired therapeutic efficacy of peripheral blood-derived progenitor cells in type 2 DM patients… CONTINUE READING