Reversal of changes of myocardial lipids by chronic administration of aspirin in isoproterenol-induced myocardial damage in rats.

@article{Manjula1992ReversalOC,
  title={Reversal of changes of myocardial lipids by chronic administration of aspirin in isoproterenol-induced myocardial damage in rats.},
  author={T S Manjula and A S Geetha and T. Ramesh and Chennam Srinivasulu Shyamala Devi},
  journal={Indian journal of physiology and pharmacology},
  year={1992},
  volume={36 1},
  pages={47-50}
}
The effect of aspirin on isoproterenol-induced changes related to myocardial damage was studied in rats. Rats were treated with aspirin (1.2 mg/100 g/day) orally, daily for a period of one month. Isoproterenol (20 mg/100 g, sc, twice at an interval of 24 hr) was administered. In isoproterenol treated rats marked increase in cholesterol, free fatty acids and triglycerides in both serum and heart were observed. The phospholipid level was lowered in heart with significant increase in serum in… CONTINUE READING

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