Reversal of cardiac complications in thalassemia major by long-term intermittent daily intensive iron chelation.

@article{Miskin2003ReversalOC,
  title={Reversal of cardiac complications in thalassemia major by long-term intermittent daily intensive iron chelation.},
  author={Hagit Miskin and Isaac Yaniv and Michael Berant and Chaim Hershko and Hannah Tamary},
  journal={European journal of haematology},
  year={2003},
  volume={70 6},
  pages={398-403}
}
OBJECTIVES In patients with thalassemia major (TM) who are non-compliant with long-term deferoxamine (DFO) chelation, survival is limited mainly because of cardiac complications of transfusional siderosis. It was recently shown in a small group of TM patients with established cardiac damage that continuous 24-h DFO infusion via an indwelling intravenous (i.v.) catheter is effective in reversing cardiac toxicity. The aim of the present study was to evaluate the results with intermittent daily (8… CONTINUE READING

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