Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine.

@article{May2002ReversalOC,
  title={Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine.},
  author={P. E. May and Annabel Barber and James T D'Olimpio and Ann Hourihane and Naji N. Abumrad},
  journal={American journal of surgery},
  year={2002},
  volume={183 4},
  pages={471-9}
}
BACKGROUND Cancer-related cachexia is caused by a diverse combination of accelerated protein breakdown and slowed protein synthesis. The hypothesis proposed in this study is that supplementation of specific nutrients known to positively support protein synthesis and reduce protein breakdown will reverse the cachexia process in advanced cancer patients. METHODS Patients with solid tumors who had demonstrated a weight loss of at least 5% were considered for the study. Patients were randomly… CONTINUE READING
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