Reversal of adriamycin resistance in human mammary cancer cells by small interfering RNA of MDR1 and MDR3 genes

@article{LanXiao2006ReversalOA,
  title={Reversal of adriamycin resistance in human mammary cancer cells by small interfering RNA of MDR1 and MDR3 genes},
  author={肖兰 LanXiao and 高瑞 RuiGao and 卢实 ShiLu and Lirong Ren 任利容 and Zehua Wang 王泽华},
  journal={Journal of Huazhong University of Science and Technology},
  year={2006},
  volume={26},
  pages={735-737}
}
The purpose of this paper is to investigate the reversal effect of small interfering RNA (siRNA) targeting MDR1 and MDR3 genes on the resistance of MCF-7/ADR cells to adriamycin. siRNA plasmid vector targeting MDR1 and MDR3 genes was transfected into MCF-7/ADR cells, and then was stained with Annexin-V FITC (fluorescein isothiocyanate conjugated) to detect… CONTINUE READING