Reversal of adenine-induced depression of mouse locomotor activity by amphetamine.


Adenine (200 mg/kg) was found to depress locomotor activity in mice. Dl-, and d-amphetamine reversed the depression of locomotor activity produced by adenine while l-amphetamine was found to be incapable of reversing the adenine-induced depression. The stimulation of mouse locomotor activity caused by dl- and d-amphetamine in mice treated with adenine was… (More)


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