Reversal of Folate Malabsorption in Tropical and Non-tropical Sprue by Calf Jejunum

@article{Baker1968ReversalOF,
  title={Reversal of Folate Malabsorption in Tropical and Non-tropical Sprue by Calf Jejunum},
  author={H. Baker and O. Frank and H. Ziffer and S. Feingold and A. A. Cintr{\'o}n-Rivera},
  journal={British Medical Journal},
  year={1968},
  volume={3},
  pages={472 - 474}
}
  • H. Baker, O. Frank, +2 authors A. A. Cintrón-Rivera
  • Published 1968
  • Medicine
  • British Medical Journal
  • In eight patients with folic acid malabsorption the malabsorption was reversed only when a combination of either 250 mg. of lyophilized human jejunal juice or 5 g. of lyophilized calf jejunum with 5 mg. of synthetic folic acid was fed; calf liver was ineffective. The factors in calf jejunum that re-established folic acid absorption were heat-stable and did not form polyglutamyl folates on previous incubation with folic acid. 
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