Revealing unique properties of the ribosome using a network based analysis

@inproceedings{DavidEden2008RevealingUP,
  title={Revealing unique properties of the ribosome using a network based analysis},
  author={Hilda David-Eden and Yael Mandel-Gutfreund},
  booktitle={Nucleic acids research},
  year={2008}
}
The ribosome is a complex molecular machine that offers many potential sites for functional interference, therefore representing a major target for antibacterial drugs. The growing number of high-resolution structures of ribosomes from different organisms, in free form and in complex with various ligands, provides unique data for structural and comparative analyses of RNA structures. We model the ribosome structure as a network, where nucleotides are represented as nodes and intermolecular… CONTINUE READING