Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses

  title={Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses},
  author={Genevi{\`e}ve Marcoux and Anne-Claire Duchez and Nathalie Cloutier and Patrick Provost and Peter A Nigrovic and Eric Boilard},
  booktitle={Scientific reports},
Extracellular vesicles (EV) are small membrane vesicles produced by cells upon activation and apoptosis. EVs are heterogeneous according to their origin, mode of release, membrane composition, organelle and biochemical content, and other factors. Whereas it is apparent that EVs are implicated in intercellular communication, they can also be used as biomarkers. Continuous improvements in pre-analytical parameters and flow cytometry permit more efficient assessment of EVs; however, methods to… CONTINUE READING


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