Revealing stable processing products from ribosome-associated small RNAs by deep-sequencing data analysis

@inproceedings{ywicki2012RevealingSP,
  title={Revealing stable processing products from ribosome-associated small RNAs by deep-sequencing data analysis},
  author={Marek Żywicki and Kamilla Bąkowska-Żywicka and Norbert Polacek},
  booktitle={Nucleic acids research},
  year={2012}
}
The exploration of the non-protein-coding RNA (ncRNA) transcriptome is currently focused on profiling of microRNA expression and detection of novel ncRNA transcription units. However, recent studies suggest that RNA processing can be a multi-layer process leading to the generation of ncRNAs of diverse functions from a single primary transcript. Up to date no methodology has been presented to distinguish stable functional RNA species from rapidly degraded side products of nucleases. Thus the… CONTINUE READING
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