Revascularization in the rabbit hindlimb: dissociation between capillary sprouting and arteriogenesis.

  title={Revascularization in the rabbit hindlimb: dissociation between capillary sprouting and arteriogenesis.},
  author={James C. Hershey and Elizabeth P. Baskin and J Douglas Glass and Hadassa Hartman and David B. Gilberto and Irene T. Rogers and Jacquelynn J. Cook},
  journal={Cardiovascular research},
  volume={49 3},
OBJECTIVE Animal models of hindlimb ischemia are critical to our understanding of peripheral vascular disease and allow us to evaluate therapeutic strategies aimed to improve peripheral collateral circulation. To further elucidate the processes involved in revascularization following ischemia, we evaluated the temporal association between tissue ischemia, vascular endothelial cell growth factor (VEGF) release, angiogenesis (capillary sprouting), arteriogenesis (growth of the larger muscular… CONTINUE READING
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